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IID-1.2 Data Details

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IID-1.2 Reduce serotype b cases of Haemophilus influenzae (Hib) invasive disease among children under age 5 years

About the Data

Description of the data source, numerator, denominator, survey questions, and other relevant details about the national estimate.

Data Source: 
Active Bacterial Core Surveillance (ABCS); Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases (CDC/NCIRD)
Population Estimates; U.S. Census Bureau (Census)
Changed Since the Healthy People 2020 Launch: 
Yes
Measure: 
per 100,000
Baseline (Year): 
0.30 (2008)
Target: 
0.27
Target-Setting Method: 
10 percent improvement
Numerator: 

Estimated number of all reported confirmed and probable cases of Haemophilus influenzae invasive disease for children under age 5 years

Denominator: 

Number of children under age 5 years

Comparable Healthy People 2010 Objective: 
Adapted from HP2010 objective
Data Collection Frequency: 
Annual
Methodology Notes: 

    FOR SINGLE DATA YEARS: Case rates are calculated based on the resident population of the ABCs surveillance areas for the data year involved. For census years (e.g. 2010), population counts enumerated as of April 1 are used. For all other years, populations estimates as of July 1 are used. Postcensal population estimates are used in rate calculations for years after a census year and match the data year vintage (e.g. July 1, 2011 resident population estimates from Vintage 2011 are used as the denominator for 2011 rates). Postcensal population estimates are used in rate calculations for the years between censuses (e.g. 1991-1999, 2001-2009).

    Data reflect cases of Hib disease among children less than 5 years of age submitted to Active Bacterial Core surveillance.

    The Active Bacterial Core surveillance (ABCs) system is an active laboratory and population-based surveillance system that provides reports of H. influenzae cases from all or parts of 10 states in the United States. ABCs is supported by the CDC as part of its Emerging Infections Program network. The population under surveillance was 36,748,349 in 2009 (representing 12.0% of the US population).

    A case was defined as isolation of H. influenzae from a normally sterile body site (eg, blood or cerebrospinal fluid) in a person aged <5 years. Illness outcome was based on patient status at the time of hospital discharge. Serotyping of H. influenzae was performed by using slide agglutination or polymerase chain reaction. All isolates from ABCs sites were sent to the CDC, where serotype was confirmed by using slide agglutination, Haemophilus quad identification plates or API Neisseria-Haemophilus strips, and polymerase chain reaction. The CDC result was used as the final serotype in the ABCs data set. This measure includes confirmed cases of H. influenzae type b disease.

Caveats and Limitations: 
ABCs Areas California (3 county San Francisco Bay area); Colorado (5 county Denver area); Connecticut; Georgia; Maryland; Minnesota; New Mexico; New York (15 county Rochester and Albany areas); Oregon; Tennessee (20 urban counties)
Changes Between HP2010 and HP2020: 
This objective differs from Healthy People 2010 objective 14-01c in that the measure was revised from a count to a rate per 100,000. In addition, the National Notifiable Disease Surveillance System (NNDSS) data source was removed, while the Active Bacterial Core Surveillance (ABCs) data source was retained.

Revision History

Any change to the objective text, baseline, target, target-setting method or data source since the Healthy People 2020 launch.

Description of Changes Since the Healthy People 2020 Launch: 
In 2013, the objective statement was changed from "aged 5 years or under" to "under age 5 years" to make the age group consistent with the numerator definition. In 2013, the National Notifiable Disease Surveillance System (NNDSS) data source was removed. NNDSS data were insufficient to assess Hib with any degree of confidence because Haemophilus influenzae serotyping information was often missing. The Active Bacterial Core Surveillance (ABCs) was retained. In 2014, Population Estimates was added as a data source to reflect measure's population denominator. The data and target were not revised.

References

Additional resources about the objective

  1. Centers for Disease Control and Prevention (CDC). Case definitions for infectious conditions under public health surveillance. Morbidity and Mortality Weekly Report 46 (RR-10), 1997. (See reference for updated case definitions.)