FS-3.3 Prevent an increase in the proportion of nontyphoidal Salmonella isolates from humans that are resistant to gentamicin
About the Data
Description of the data source, numerator, denominator, survey questions, and other relevant details about the national estimate.
Number of non-typhoidal Salmonella isolates that are resistant to gentamicin
Number of non- typhoidal Salmonella isolates tested for resistance to gentamicin
The primary objectives of NARMS are to:
- Monitor trends in antimicrobial resistance among foodborne bacteria from humans, retail meats, and animals
- Disseminate timely information on antimicrobial resistance to promote interventions that reduce resistance among foodborne bacteria
- Conduct research to better understand the emergence, persistence, and spread of antimicrobial resistance
- Assist the FDA in making decisions related to the approval of safe and effective antimicrobial drugs for animals
In 1996, surveillance for Salmonella in NARMS began in 14 sites. Since 2003, all 50 states have been participating, which represent a population of approximately 321 million (US Census Bureau, 2015). Participating sites forward every Salmonella serotypes Typhi and Paratyphi A, every twentieth non-typhoidal Salmonella, every twentieth Shigella, and every twentieth E. coli O157 isolates received at their public health laboratories to NARMS at CDC for susceptibility testing.
Susceptibility testing involves determination of minimum inhibitory concentrations for antimicrobial agents, including: ampicillin, amoxicillin-clavulanic acid, azithromycin, cefoxitin, ceftriaxone, chloramphenicol, ciprofloxacin, gentamicin, nalidixic acid, streptomycin, sulfisoxazole, tetracycline, and trimethoprim-sulfamethoxazole. Resistance in non-typhoidal Salmonella is used for this objective. Non-typhoidal Salmonella excludes the following typhoidal Salmonella serotypes: Typhi, Paratyphi A, Paratyphi B (i.e., tartrate negative isolates), and Paratyphi C. Tartrate positive Salmonella serotype Paratyphi B isolates are referred to as Salmonella serotype Paratyphi B var. L(+) tartrate+ and are not typically associated with typhoidal disease.
Any change to the objective text, baseline, target, target-setting method or data source since the Healthy People 2020 launch.
Additional resources about the objective
National Antimicrobial Resistance Monitoring System
National Antimicrobial Resistance Monitoring System for Enteric Bacteria