Post-exposure Passive Immunization for Preventing Rubella and Congenital Rubella Syndrome
Description of Resource:
One way of preventing rubella in people who come into contact with a contagious person is to inject them with antibodies from blood donations. This systematic review sought to evaluate whether this is effective and included 12 studies in high-income countries. Eleven studies compared injecting antibodies into the muscle or vein of participants to injecting salt water or giving no treatment. These studies found antibodies to be effective at preventing rubella. People given antibodies were 39% less likely to develop rubella than people not given antibodies. People who received the highest doses of antibodies were 80% less likely to develop rubella than people not given antibodies.