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Evidence-Based Resource Summary

Strength of Evidence: 
4 out of 4
4 out of 4
Year Published: 

Physical Exercise Training Interventions for Children and Young Adults During and After Treatment for Childhood Cancer

Description of Resource: 
Decreased physical fitness has been reported in patients and survivors of childhood cancer. This systematic review aimed to evaluate the effect of a physical exercise training intervention on the physical fitness of children with cancer within 5 years of their diagnosis, compared to a control group of children with cancer who did not receive an exercise intervention. It identified 6 studies involving a total of 171 participants with acute lymphoblastic leukemia. It found some small benefits of physical exercise training on body composition, flexibility, cardiorespiratory fitness, muscle strength, and quality of life. The evidence was limited and more studies are needed to assess the effects of exercise in a variety of childhood cancer populations.

Evidence-Based Resource Details

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Developed By: 
Cochrane Review
Developer Type: 
Non-Federal Government
Healthy People 2020 Topic Area(s): 
Physical Activity
Healthy People 2020 Objectives: 
Resource Type: 
Systematic Review
Braam KI, van der Torre P, Takken T, Veening MA, van Dulmen-den Broeder E, Kaspers GJL. Physical exercise training interventions for children and young adults during and after treatment for childhood cancer. Cochrane Database Syst Rev [Internet]. 2016 [cited 2018 Apr 30];(3). Art. No.: CD008796. doi: 10.1002/14651858.CD008796.pub3. Available from: