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Evidence-Based Resource Summary

Strength of Evidence: 
4 out of 4
4 out of 4
Year Published: 

Medication Review in Hospitalised Patients to Reduce Morbidity and Mortality

Description of Resource: 
Older adults are often prescribed several drugs despite a higher risk of adverse events in this population. Medication review involves evaluating the therapeutic effectiveness and harms of each drug in relation to the individual patient and condition it treats. This systematic review aimed to assess whether delivery of a medication review by a physician, pharmacist, or other health care professional leads to improved health outcomes for hospitalized adult patients compared with standard care. It identified 10 trials involving 3,575 participants. It found no evidence that medication review reduces mortality or hospital readmissions. However, it did find evidence that medication review may reduce emergency department contacts. High-quality trials with long-term follow-up are needed to provide more definitive evidence for the effect of medication review on clinically important outcomes.

Evidence-Based Resource Details

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Developed By: 
Cochrane Review
Developer Type: 
Non-Federal Government
Healthy People 2020 Topic Area(s): 
Medical Product Safety
Healthy People 2020 Objectives: 
Resource Type: 
Systematic Review
Christensen M, Lundh A. Medication review in hospitalised patients to reduce morbidity and mortality. Cochrane Database Syst Rev [Internet]. 2016 [cited 2018 Feb 28];(2). Art. No.: CD008986. doi: 10.1002/14651858.CD008986.pub3. Available from: