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Evidence-Based Resource Summary

Strength of Evidence: 
4 out of 4
4 out of 4
Year Published: 

Interventions for Smokeless Tobacco Use Cessation

Description of Resource: 
Use of smokeless tobacco (ST) can lead to tobacco dependence, and long-term use can lead to health problems including periodontal disease, cancer, and cerebrovascular and cardiovascular disease. This Cochrane review aimed to assess the effects of behavioral and drug therapy interventions for the treatment of ST use. This systematic review identified 34 randomized trials covering over 16,000 participants. Sixteen trials with 3,722 participants tested drug therapies. The evidence suggests that the nicotine lozenge might help people quit, but the quality of evidence was low and more research is needed. Seventeen trials with 12,394 participants tested behavioral support. This systematic review could not determine what important elements of effective support were, but providing access to telephone support generally seemed to be helpful.

Evidence-Based Resource Details

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Developed By: 
Cochrane Library
Developer Type: 
Non-Federal Government
Healthy People 2020 Topic Area(s): 
Tobacco Use
Healthy People 2020 Objectives: 
Resource Type: 
Systematic Review
Ebbert JO, Elrashidi MY, Stead LF. Interventions for smokeless tobacco use cessation. Cochrane Database of Systematic Reviews 2015, Issue 10. Art. No.: CD004306. doi: 10.1002/14651858.CD004306.pub5. Available from: