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Evidence-Based Resource Summary

Strength of Evidence: 
4 out of 4
4 out of 4
Year Published: 

Hormone Therapy for Preventing Cardiovascular Disease in Post-menopausal Women

Description of Resource: 
Hormone therapy is used for controlling menopausal symptoms. It has also been used for the prevention of cardiovascular disease in post-menopausal women. This systematic review assessed the effects of using hormone therapy for 6 months or more in preventing cardiovascular disease. Nineteen randomized controlled trials were identified that compared oral hormone therapy with placebo. This review found no evidence that hormone therapy provides any protective effects. Rather, hormone therapy in post-menopausal women increased the risk of stroke and obstruction of a vein by a blood clot.

Evidence-Based Resource Details

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Developed By: 
Cochrane Review
Developer Type: 
Non-Federal Government
Healthy People 2020 Topic Area(s): 
Heart Disease and Stroke
Healthy People 2020 Objectives: 
Resource Type: 
Systematic Review
Boardman HMP, Hartley L, Eisinga A, Main C, Roqué i Figuls M, Bonfill Cosp X, Gabriel Sanchez R, Knight B. Hormone therapy for preventing cardiovascular disease in post-menopausal women. Cochrane Database Syst Rev [Internet]. 2015 [cited 2017 Dec 29];(3). Art. No.: CD002229. doi: 10.1002/14651858.CD002229.pub4. Available from: