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Evidence-Based Resource Summary

Strength of Evidence: 
4 out of 4
4 out of 4
Year Published: 
2013

Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility – Women Who Have Family Members with Breast, Ovarian, Tubal, or Peritoneal Cancer

Description of Resource: 
The U.S. Preventive Services Task Force recommends that primary care providers screen women who have family members with breast, ovarian, tubal, or peritoneal cancer with 1 of several screening tools designed to identify a family history that may be associated with an increased risk for potentially harmful mutations in breast cancer susceptibility genes (BRCA1 or BRCA2). Women with positive screening results should receive genetic counseling and, if indicated after counseling, BRCA testing.

Evidence-Based Resource Details

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Developed By: 
U.S. Preventive Services Task Force
Developer Type: 
Federal Government
Healthy People 2020 Objectives: 
Resource Type: 
Systematic Review
Citation: 
Nelson HD, Huffman LH, Fu R, Harris EL. Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: systematic evidence review for the U.S. Preventive Services Task Force [Internet]. 2005 [cited 2013 Feb 27]. First published in Ann Intern Med Sep 6;143(5):362–79. Available from: http://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing