Fibrates for Primary Prevention of Cardiovascular Disease Events
Description of Resource:
Cardiovascular disease is the most common cause of death, illness, disability, and reduced quality of life in industrialized countries. Fibrates are a class of drugs that work by positively influencing fats in the blood. This systematic review sought to evaluate the benefits and harms of using fibrate treatment compared to placebo or usual care for preventing cardiovascular disease in people at increased risk of developing cardiovascular disease. This review identified 6 trials and found a risk reduction of 16% with fibrate therapy for the combined outcome of death due to cardiovascular disease, heart attack, or stroke.