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Evidence-Based Resource Summary

Strength of Evidence: 
4 out of 4
4 out of 4
Year Published: 

Drugs for Preventing Malaria in Pregnant Women in Endemic Areas: Any Drug Regimen versus Placebo or No Treatment

Description of Resource: 
Pregnancy increases the risk of malaria. Malaria is associated with poor health outcomes for both the mother and the infant, especially during the first or second pregnancy. For this reason, women are encouraged to try to prevent malaria infection during pregnancy by sleeping under mosquito bed nets, and by taking drugs effective against malaria throughout pregnancy as chemoprevention. This systematic review identified 17 trials and sought to quantify the overall effects of chemoprevention. For women in their first or second pregnancy, malaria chemoprevention prevented moderate to severe anemia, and malaria parasites were not detected in their blood. In their infants, malaria chemoprevention improved the average birth weight and reduced the number of low birth weight infants.

Evidence-Based Resource Details

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Developed By: 
Cochrane Review
Developer Type: 
Non-Federal Government
Healthy People 2020 Topic Area(s): 
Global Health
Healthy People 2020 Objectives: 
Resource Type: 
Systematic Review
Radeva-Petrova D, Kayentao K, ter Kuile FO, Sinclair D, Garner P. Drugs for preventing malaria in pregnant women in endemic areas: Any drug regimen versus placebo or no treatment. Cochrane Database Syst Rev [Internet]. 2014 [cited 2017 12 5];(10):Article CD000169. doi: 10.1002/14651858.CD000169.pub3. Available from: