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Evidence-Based Resource Summary

Strength of Evidence: 
4 out of 4
4 out of 4
Year Published: 
2019

BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing in Women at Increased Risk

Description of Resource: 
The U.S. Preventive Services Task Force (USPSTF) recommends that primary care clinicians assess women with a personal or family history of breast, ovarian, tubal, or peritoneal cancer or who have an ancestry associated with breast cancer susceptibility 1 and 2 (BRCA1/2) gene mutations with an appropriate brief familial risk assessment tool. Women with a positive result on the risk assessment tool should receive genetic counseling and, if indicated after counseling, genetic testing. This is a B recommendation, which means the USPSTF recommends the service. There is high certainty that the net benefit is moderate or there is moderate certainty that the net benefit is moderate to substantial.

Evidence-Based Resource Details

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Developed By: 
U.S. Preventive Services Task Force
Developer Type: 
Federal Government
Healthy People 2020 Topic Area(s): 
Cancer
Genomics
Healthy People 2020 Objectives: 
Resource Type: 
Systematic Review
Citation: 
U.S. Preventive Services Task Force. BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing recommendation statement [Internet]. 2019 Aug [cited 2019 Aug 21]. Available from: https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing1