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Evidence-Based Resource Summary

Strength of Evidence: 
4 out of 4
4 out of 4
Year Published: 
2014

Beta-Blockers for Preventing Stroke Recurrence

Description of Resource: 
Beta-blockers are drugs that reduce heart rate and blood pressure, and have other effects that might also reduce the risks of stroke and heart attack. This systematic review sought to evaluate the efficacy of beta-blockers for preventing stroke recurrence and for reducing death and major vascular events in people with a previous stroke or transient ischemic attack (TIA), and to determine their safety. This review identified 2 high quality trials and found no clear evidence that beta-blockers reduced the risk of stroke, heart attack, or death from vascular disease. Participants who received beta-blockers instead of placebo showed significantly more adverse effects. More studies with larger samples are needed.

Evidence-Based Resource Details

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Developed By: 
Cochrane Review
Developer Type: 
Non-Federal Government
Healthy People 2020 Topic Area(s): 
Heart Disease and Stroke
Healthy People 2020 Objectives: 
Resource Type: 
Systematic Review
Citation: 
De Lima LG, Saconato H, Atallah ÁN, da Silva EMK. Beta-blockers for preventing stroke recurrence. Cochrane Database Syst Rev [Internet]. 2014 [cited 2017 Dec 29];(10). Art. No.: CD007890. doi: 10.1002/14651858.CD007890.pub3. Available from: http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007890.pub3/full