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Evidence-Based Resource Summary

Strength of Evidence: 
4 out of 4
4 out of 4
Year Published: 

Antenatal Lower Genital Tract Infection Screening and Treatment Programs for Preventing Preterm Delivery

Description of Resource: 
Genital tract infections can cause preterm labor, which is associated with infant death. This systematic review aimed to determine the effect of screening for infections during pregnancy on the number of premature births. One study was identified. It involved 4,155 women who: were at 37 or fewer weeks gestation; were not in labor; had no vaginal bleeding; and had no symptoms of lower genital tract infection. The intervention group was screened and treated for genital tract infections. The control group was also screened, but the screening results were not revealed. The screening program reduced preterm births from 5% in the control group to 3% in the intervention group, and also reduced the incidence of low birth weight in the intervention group. Future trials should evaluate the effects of different types of infection screening programs.

Evidence-Based Resource Details

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Developed By: 
Cochrane Review
Developer Type: 
Non-Federal Government
Healthy People 2020 Topic Area(s): 
Maternal, Infant, and Child Health
Healthy People 2020 Objectives: 
Resource Type: 
Systematic Review
Sangkomkamhang US, Lumbiganon P, Prasertcharoensuk W, Laopaiboon M. Antenatal lower genital tract infection screening and treatment programs for preventing preterm delivery. Cochrane Database Syst Rev [Internet]. 2015 [cited 2018 Feb 28];(2). Art. No.: CD006178. doi: 10.1002/14651858.CD006178.pub3. Available from: