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Evidence-Based Resource Summary

Strength of Evidence: 
4 out of 4
4 out of 4
Year Published: 

Altered Dietary Salt Intake for People with Chronic Kidney Disease

Description of Resource: 
People with chronic kidney disease (CKD) are at increased risk of heart disease and worsening kidney health, which can lead to a need for dialysis or kidney transplantation to survive. High salt intake is linked to risk factors for both heart disease and worsening kidney function, including high blood pressure. This Cochrane review aimed to find out if altering salt in the diet was beneficial for people with CKD. It found that reducing salt intake reduced 24-hour sodium excretion and blood pressure. There was no significant difference in kidney function measures or body weight and there was no significant change in total cholesterol or hypotension. The review was unable to determine the direct effects of sodium restriction on outcomes such as mortality and progression to end-stage kidney disease.

Evidence-Based Resource Details

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Developed By: 
Cochrane Library
Developer Type: 
Non-Federal Government
Healthy People 2020 Topic Area(s): 
Chronic Kidney Disease
Healthy People 2020 Objectives: 
Resource Type: 
Systematic Review
McMahon EJ, Campbell KL, Bauer JD, Mudge DW. Altered dietary salt intake for people with chronic kidney disease. Cochrane Database of Systematic Reviews 2015, Issue 2. Art. No.: CD010070. doi: 10.1002/14651858.CD010070.pub2. Available from: