State Public Health Laboratories Performing Antiviral Resistance Testing
The only current treatments available for people suffering from influenza infection are antivirals. Every season, influenza viruses evolve to evade the collective immune system of a population. Because of this, it is possible that newly emergent and seasonal strains will become resistant to these medications. The purpose of this surveillance is to monitor for these mutations and to alert public-health officials if and when these antiviral-resistant strains become a widely circulating strain.
The ARPE report is an annual summary of the core activities of eliciting and evaluating contacts to TB cases and treating the contacts that have latent TB infection (LTBI). The designated individual at the TB control jurisdiction for APRE reporting collects the data throughout the year and reports an aggregate of these data annually to the CDC.
The data are accumulated into a cohort over 1 calendar year (i.e. January 31, 2009-December 31, 2009). The contacts are assigned to the same count-year as the TB cases being investigated (i.e. January 31, 2009-December 31, 2009). A preliminary report should be tabulated by August 15 following the cohort year (i.e., before all the completion-of-therapy data are available; 2010) and, The final results, including the completion-of-therapy data, are due in aggregate form via the ARPE form at CDC by August 15, 1 year later (i.e. 2011).
Annual reporting of these data from the federally funded TB control jurisdictions to CDC may vary; for example, in 2009, of the 60 TB control jurisdictions collecting contact investigation data, 55 submitted ARPE reports to the CDC. The response rate for the TB control jurisdictions was 91.6%.