National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance Project
The National Electronic Injury Surveillance Sustem -- Cooperative Adverse Drug Event Surveillance Project (NEISS-CADES) is an expansion of the Consumer Product Safety Commission's (CPSC) National Electronic Injury Surveillance System (NEISS), used to monitor consumer-product related injuries. NEISS-CADES collects data on all adverse drug events (ADEs) treated in U.S. hospital emergency departments, whether or not associated with consumer products. NEISS data are collected from a nationally representative sample of U.S. hospital emergency departments; NEISS-CADES uses a subsample of those emergency departments for its data collection.
NEISS hospitals are a stratified probability sample of all U.S. hospitals that have at least 6 beds and provide 24 hour emergency department (ED) services. The NEISS-CADES data are collected at a subset of these hospitals and include very large inner-city hospitals with trauma centers, as well as large urban, suburban, rural, and children's hospitals. Trained onsite hospital coders abstract and code data for all cases of adverse drug events (ADEs) treated in the hospital ED. ADEs are defined as an injury related to the outpatient use of a drug resulting from allergic reaction, side effect, unintentional overdose or secondary effect. Intentional drug injuries (e.g., suicide attempts) and injuries resulting from alcohol, tobacco, or illicit drug use are excluded. Data are weighted to produce national estimates.
NEISS collects data from a sample of 100 hospitals with 24 hour emergency department services. NEISS-CADES data are collected at 64 of these hospitals.
Mendelsohn, AB: The National Electronic Injury Surveillance System: Cooperative Adverse Drug Events Surveillance System (NEISS-CADES). May 18, 2005. Powerpoint slides; available at: Evaluation and overview of the National Electronic Injury Surveillance System-Cooperative Adverse Drug Event Surveillance Project (NEISS-CADES).