Pregnant women who are infected with syphilis can transmit the infection to the fetus causing congenital syphilis (CS) with serious adverse outcomes of the pregnancy in at least 50% of the cases. Elimination of congenital syphilis would contribute importantly to reduction of lost pregnancies, preterm/low birthweight infants and prenatal death.
Although the numbers and rates of CS have been declining in the United States, there is a danger of a resurgence should syphilis recur among heterosexual populations. Yet, unlike many neonatal infections, this is a preventable disease which could be eliminated through effective antenatal screening and treatment of infected pregnant women.
A minimum of 500 valid test results by gender and subpopulation is recommended to derive reliable estimates for this measure. Some clinics may not collect all U.S. Census-defined race and/or ethnicity data categories. Data are based on CDC congenital syphilis (CS) case investigation and report, Form 73.126.
The original baseline was revised from 10.1 to 10.7 due to reporting delays. The target was adjusted from 9.1 to 9.6 to reflect the revised baseline using the original target setting method.