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IID-4.3 Data Details

IID-4.3 Reduce invasive antibiotic-resistant pneumococcal infections among children under age 5 years

About the Data

Description of the data source, numerator, denominator, survey questions, and other relevant details about the national estimate.

National Data Source
Active Bacterial Core Surveillance (ABCS); Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases (CDC/NCIRD)
Changed Since the Healthy People 2020 Launch
Yes
Measure
per 100,000 
Baseline (Year)
8.3 (2008)
Target
6.0
Target-Setting Method
Projection/trend analysis
Numerator
Number of children under age 5 years with a laboratory-confirmed invasive antibiotic-resistant pneumococcal infection in the past 12 months
Denominator
Number of children under age 5 years
Data Collection Frequency
Annual
Comparable Healthy People 2010 Objective
Adapted from HP2010 objective
Methodology Notes

A laboratory-confirmed invasive antibiotic-resistant pneumococcal infection is defined as the isolation of Streptococcus pneumoniae, from a normally sterile site (blood, cerebral spinal fluid, etc.), that is not susceptible to penicillin, amoxicillin, erythromycin, cefotaxime, ceftriaxone, cefuroxime, tetracycline, vancomycin, or levofloxacin according to the 2012 breakpoints defined by the Clinical and Laboratory Standards Institute.

Missing race data was multiply imputed and surveillance rates were standardized to the racial distribution of the US population using the NCHS bridged-race vintage 2010 postcensal file.

Caveats and Limitations
ABCs Areas California (San Francisco County and children < 5 years in Alameda and Contra Costa counties); Colorado (5 county Denver area); Connecticut; Georgia (20 county Atlanta area); Maryland (6 county Baltimore area); Minnesota; New Mexico; New York (15 county Rochester and Albany areas and children <5 years in Erie county); Oregon (3 county Portland area); Tennessee (20 counties) ABCs Population The surveillance areas represent 29,757,552 persons. Source: National Center for Health Statistics bridged-race vintage 2010 postcensal file

Revision History

Any change to the objective text, baseline, target, target-setting method or data source since the Healthy People 2020 launch.

Description of Changes Since the Healthy People 2020 Launch

In 2013, the objective statement changed from "Reduce invasive penicillin-resistant pneumococcal infections among children under age 5 years" to "Reduce invasive antibiotic-resistant pneumococcal infections among children under age 5 years." Doctors use many drugs to treat pneumococcal infections. Although penicillin still works well, it is not used often because other drugs can be taken once a day instead of four times a day. To make the HP2020 measure more useful to doctors and patients, CDC would like to include infections that are resistant to several antibiotics, not just penicillin. The numerator definition was revised accordingly. The baseline was recalculated and was revised from 4.3 to 8.2. The target was also recalculated and was revised from 3.0 to 6.0.

References

Additional resources about the objective.

  1. Centers for Disease Control and Prevention (CDC). Active Bacterial Core surveillance (ABCs), http://www.cdc.gov/abcs.