Description of the data source, numerator, denominator, survey questions, and other relevant details about the national estimate.
A laboratory-confirmed invasive antibiotic-resistant pneumococcal infection is defined as the isolation of Streptococcus pneumoniae, from a normally sterile site (blood, cerebral spinal fluid, etc.), that is not susceptible to penicillin, amoxicillin, erythromycin, cefotaxime, ceftriaxone, cefuroxime, tetracycline, vancomycin, or levofloxacin according to the 2012 breakpoints defined by the Clinical and Laboratory Standards Institute.
Missing race data was multiply imputed and surveillance rates were standardized to the racial distribution of the US population using the NCHS bridged-race vintage 2010 postcensal file.
Any change to the objective text, baseline, target, target-setting method or data source since the Healthy People 2020 launch.
In 2013, the objective statement changed from "Reduce invasive penicillin-resistant pneumococcal infections among children under age 5 years" to "Reduce invasive antibiotic-resistant pneumococcal infections among children under age 5 years." Doctors use many drugs to treat pneumococcal infections. Although penicillin still works well, it is not used often because other drugs can be taken once a day instead of four times a day. To make the HP2020 measure more useful to doctors and patients, CDC would like to include infections that are resistant to several antibiotics, not just penicillin. The numerator definition was revised accordingly. The baseline was recalculated and was revised from 4.3 to 8.2. The target was also recalculated and was revised from 3.0 to 6.0.
Additional resources about the objective.
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