Description of the data source, numerator, denominator, survey questions, and other relevant details about the national estimate.
The estimated number of births to HBV-infected mothers is derived by applying race- and ethnicity- specific estimates of the prevalence of hepatitis B surface antigen to NVSS-N annual natality data.
Using data collected by the Perinatal Hepatitis B Prevention Program and NVSS-N, this measure is based on the following estimation procedure:
Multiply the total births per year to HBsAg- positive women by the proportion of pregnant women screened for HBsAg and then by the proportion of infants born to identified HBsAg- positive women who receive the vaccine (this estimates the number of infants who were born to identified HBsAg-positive women and received at least one dose of vaccine). Multiply the total number of infants who were born to HBsAg-positive women and received at least one dose of vaccine by the proportion of vaccinated infants who will remain susceptible, and add to the number of infants born to HBsAg-positive women who are not vaccinated (this estimates the number of infants born to HBsAg-positive women who remain susceptible). Finally, multiply number of infants born to HBsAg- positive women remaining susceptible by the proportion of susceptible infants who will become infected and then by the proportion of infected infants who will remain chronically infected with HBV.
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