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HAI-2 Data Details

HAI-2 Reduce invasive healthcare-associated methicillin-resistant Staphylococcus aureus (MRSA) infections

About the Data

Description of the data source, numerator, denominator, survey questions, and other relevant details about the national estimate.

National Data Source
Active Bacterial Core Surveillance (ABCS); Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases (CDC/NCIRD)
Changed Since the Healthy People 2020 Launch
per 100,000 
Baseline (Year)
27.08 (2007-2008)
Target-Setting Method
Maintain consistency with national programs, regulations, policies, and laws.
Number of cases of invasive healthcare-associated methicillin-resistant Staphylococcus aureus infections
Number of persons
Questions Used to Obtain the National Baseline Data

From the Emerging Infections Program (EIP) network Active Bacterial Core surveillance:


A case is defined as a current resident of the ABCs MRSA catchment area during the calendar years of 2007 or 2008, and who had a positive invasive culture reported to the EIP site. Questions used to collect these data are from the EIP/ABCs MRSA Surveillance Case Report Form. The following questions were used to collect gender and race of each patient:


  1. Male
  2. Female


  1. American Indian or Alaskan Native
  2. Asian, Black or African American
  3. Native Hawaiian or Other Pacific Islander
  4. White
  5. Unknown
Data Collection Frequency
Methodology Notes

Healthcare-associated MRSA is defined as a patient who had one or any combination of the following: an invasive MRSA culture collected 3 or more calendar days after the date of hospital admission, a hospitalization, surgery, dialysis, or was a resident of a long-term care facility in the previous year before date of initial culture, or the presence of a central vascular catheter around the time of hospital admission. Invasive is defined as an isolate of MRSA cultured from a normally sterile site, such as blood, cerebrospinal fluid (CSF), pleural fluid, peritoneal fluid, pericardial fluid, joint or synovial fluid, bone, an internal organ.

Caveats and Limitations
The number of reporting units varies as new hospitals open, close or consolidate within the 10 site, 15 million person surveillance catchment area. Additionally, if there is a reduction in funding, the surveillance catchment area may be reduced accordingly. Because MRSA cases are detected from several sources (i.e., referral laboratories, non-hospital institutions, dialysis referral laboratories, etc.), tracking the number of facilities yearly is not meaningful; instead, CDC prefers to utilize the population under surveillance.
Target Calculation Methods
Target is consistent with DHHS Action Plan to Prevent Healthcare-Associated Infections targets and metrics. The suggested target is a 75% reduction of HAI infections by year 2020. A two-year baseline (2007-2008) was chosen to increase the accuracy of the single point estimate by which an annual change would be measured, to increase precision of the referent period.

Revision History

Any change to the objective text, baseline, target, target-setting method or data source since the Healthy People 2020 launch.

Description of Changes Since the Healthy People 2020 Launch

In 2012, the baseline was revised from to 26.24 to 27.08 per 100,000 population due to data source changes in methodology: data are adjusted for sex and receipt of chronic dialysis, in addition to age and race. The target remains unchanged.