Description of the data source, numerator, denominator, survey questions, and other relevant details about the national estimate.
Down syndrome includes cytogenetically confirmed full trisomy and translocation but excludes mosaic Down syndrome. Down syndrome diagnosis is obtained using either ICD-9 (confirmed 758.0, EXCLUDE mosaic Down syndrome) or CDC/BPA (758.000, 758.010, 758.020, 758.030, EXCLUDE 758.040 (mosaic Down syndrome), 758.090 (Down syndrome, NOS) codes. Fourteen state birth defects surveillance programs contributed data.
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